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596 Uppsatser om Clinical trials - Sida 1 av 40

Vaccination mot Humant Papillomvirus - vem bör vaccineras?

Background: Infection with Human Papillomavirus, HPV, is one of the world's most common sexual transmitted infections. The virus causes genital warts (condyloma) but certain virus types can cause cancer. The most common cancer type caused by the virus is cancer of the cervix. Nowadays there is a screening program for women between 23 and 60 years of age where Pap smears of the cervix is taken to discover abnormalities at an early stage. Cervical cancer is very common all over the world and this screening program saves many lives, but not in the less developed countries since the screening program is too expensive.

Effekt av tillskott med isoflavonoider från sojabönor på LDL-kolesterol hos vuxna - En systematisk översikt

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Effects of isoflavone supplementation from soybeans on LDL-cholesterol levels in adultAuthors: Malin Blomgren Alegria and Ruut ReivaaraSupervisor: Lena HulthénExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2013-04-08Background: One of the most common causes of death in Sweden is due to cardiovascular diseases such as heart attack and stroke. Hypercholesterolemia is one of the risk factors for cardiovascular disease. In Asia, hypercholesterolemia is less common than in the Western countries. In Asian countries, soy products are consumed in larger quantities than in the Western world, which has led to implemented research with the intention of examining soy's potential effect on cholesterol levels.Objective: To investigate whether there is scientific evidence that isoflavone supplementation from soy bean may have a lowering effect on LDL-cholesterol.Search strategy: The databases used for the systematic literature search were PubMed, Scopus and Cochrane. Keywords used were cholesterol and 9 versions of this, and isoflavones and 11 versions of that.Selection criteria: RCT articles, on humans, written in English, published from 2011 onwards, that focused on interventions with isoflavones from soybeans and its effect on blood cholesterol, the participants were over 18 years old and the study time was at least 24 weeks.

Åkertistel : biologi och icke-kemisk bekämpning

A growing problem in Swedish herbicide free agriculture, the Canadian thistle has been the object of several new trials, seeking methods for non-chemical weed control. The new trials have mainly confirmed earlier experiences; that the most successful methods of control are springtime ploughing, repeated cutting and competition from a stout crop. Row hoeing has also been proven effective. As opposed to earlier recommendations, half season fallow has shown to be a risky and often ineffective method of control. Trials regarding biological methods have shown that above others thistle rust (Puccinia punctiformis) may have the potential of controlling Canadian thistle the future. .

Nordingrå, maj 1675 : en ångermanländsk socken i centrum för trolldomsprocesserna

In May 1675, the local court in the northern Swedish parish of Nordingrå, which had approximately 1,000 inhabitants, held a preliminary investigation on 113 persons accused of witch-craft and superstition. For the majority of the 113, the main accusation was to have travelled to Blåkulla, a place where witches according to Swedish folklore participated in satanic festivities and rites led by the Devil himself. The preliminary investigation was held at the request of The Royal Witch-craft Commission. Nordingrå belonged to the province of Ångermanland, one of the Swedish provinces with the highest number of witch trials in the 1670s. The trials in Nordingrå have, more or less never been examined before, mainly due to the fact that no sentences or penalties were ever imposed.The purpose of this paper is to examine social relations and social conflicts in Nordingrå with the records from the witch trial 1675 as the primary source.

Sjuksköterskestudenters upplevelser av handledning under verksamhetsförlagd utbildning VFU : en empirisk undersökning

Background: The education for becoming a registered nurse in Sweden includes compulsory time for clinical practice. The clinical education means an essential part in the students? personal development. According to regulation for nurses, a registered nurse has the responsibility to supervise nurse students during their clinical placement.Aim:. The aim of the examination was to describe nurse students´ experiences of supervision during clinical education.Method: The study was an empirical examination based on interviews with seven nurse students.Results: The result showed that nurse students wanted to be seen and treated as colleagues, but not used as labour.

Plantar fasciit ? evidens för stötvågsbehandling för smärtlindring och förbättrad funktion, en systematisk litteraturstudie?

AimThe aim of the present study was to study possible evidence for shock wave therapy on pain and function in patients with plantar fasciitis.Questions1. Does shock wave therapy reduce pain in patients with plantar fasciitis?2. Does shock wave therapy improve function in patients with plantar fasciitis?MethodA systematic review of the literature was performed in the databases PubMed, EMBASE, Cochrane and Cinahl.

Resultat från tre klonförsök med fågelbär, Prunus avium L, i södra Sverige :

This study was based on measurements of growth and shape of 50 clones of wild cherry, Prunus avium L, in south Sweden and aimed at finding out wether or not any of these clones are useful for commercial propagation. Initially, a short assembly of documented knowledge concerning wild cherry as a timber producing tree species was put together. The study of the 50 clones includes information gathered during the fall of 2006 from four trials located in the counties of Blekinge, Småland and Västergöland. The oldest trial, founded in Tranemåla, Blekinge, in 1992, was focused on offspring and aimed at discerning differences between provenances and at developing an adapted plant material. The other experiments were both clone trials and founded in 2002. These are based on 50 individuals selected from the offspring trial in Tranemåla.

Alfa-linolensyra från linfröolja och dess påverkan på blodtrycket -En systematisk översiktsartikel

Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Alpha-linolenic acid from flaxseed oil and effects on blood pressure ? A systematic reviewAuthor: Christine Hårdfelt och Liduina van SitterenSupervisor: Helen LindqvistExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 9th, 2014Background: High blood pressure is strongly associated with an increased risk of developing cardiovascular disease, particularly stroke. ALA-fatty acids have previously been associated with decreased blood pressure. Flaxseed oil is very rich in these fatty acids and has also been highlighted as an affordable and sustainable source.Objective: To investigate whether ALA-fatty acids from flaxseed oil may affect blood pressure in people with high risk for cardiovascular disease.Search strategy: Two searches in PubMed and Scopus were performed. The sample was specified by using specific keywords.Selection criteria: The criteria for inclusion of studies required that flaxseed oil was compared with a control and that blood pressure was measured as an endpoint.

Klinisk gradering av hästens luftvägsstatus : en jämförande studie av kliniska graderingsprotokoll samt deras relation till luftvägshälsa och neutrofilförekomst i BAL-vätska

Respiratory disease with airway inflammation as main characteristic is common in the horse. It is a syndrome that is not yet fully understood. The etiology, pathogenesis and classification into different disease states are subjects for discussion and under continuous revision. Despite a number of modern techniques, the diagnostic procedure is challenging. There is no test considered to be gold standard when diagnosing these diseases.

Effekt av ACE-hämmare på incidens av hjärt-kärlsjukdom och mortalitet hos diabetiker typ 2 samt av diabetes hos hypertonipatienter.

Background: Diabetes mellitus is a chronic disease that manifests as an increased level of glucose in the blood. According to the World Health Organization (WHO), 347 million people have diabetes worldwide. In year 2004, 3.4 million people died from the consequences of high blood glucose. In the Swedish population the prevalence of diabetes is estimated to 3-4 %, out of which 85-90% are Type 2. Among senior citizens a prevalence of diabetes is seen in Sweden up to 14 - 15%.

Vaselin som kontroll vid försök med 1 % väteperoxidkräm i färska hudsår på häst

Wounds on horses are common and sometimes difficult to treat. The wounds are often big and could be discovered too late for primary sutures, which have to be applied within 8 hours from time of accident, before bacteria has been able to infiltrate the surrounding tissue. The healing is often complicated by delayed healing and wound infection with consequences like phlegmone, fistulation and proud flesh formation.To avoid these consequences, the traditional practice has been to administer systemic antibiotics alone, systemic antibiotics in combination with topical antibiotics or topical antibiotics alone. Because few antibiotics can be used in horses, is it important to household with the few substances that are available. In veterinary medicine today, the increasing resistance amongst pathogenic microbes such as MRSA presents a growing problem.

Innebörden av god handledning bland sjuksköterskestudenter i verksamhetsförlagd utbildning

Supervision has a strong impact on students` professional development. It is during clinical education that students will receive help in linking theory and practice. This study aimed to describe the meaning of good supervision among nursing students in clinical practice. A qualitative design was used. Nine nursing students in western Sweden, who had all experienced good supervision in clinical practice, were interviewed.The interviews were analyzed using a descriptive phenomenological methodology.The meaning of the phenomenon, good supervision in clinical education among nursing students, was shown as the students were gradually piloted to increased responsibility.

Flockning och förtjockning i High-Rate-förtjockare ? en jämförelse med konventionell förtjockarteknik och lamellsedimentering.

In the process laboratory of Metso minerals (Sala) AB, continuous tests have been made with a laboratory unit High-Rate thickener. The tests are made in order to compare three methods of thickening techniques of suspended solids. The three techniques are High-Rate thickening, conventional thickening and lamella thickening. The High-Rate and the conventional trials are based on a continuous method, while the lamella thickener is based on batch trials. Because the lamella thickener is based on batch trials and there were some optimization problems with the adding point of the flocculant at the continuous trials, it was not feasible to compare the lamella thickener with the other two thickener types.

Motstånd - inte tröst. En studie om förståelsen av motståndsbegreppet

Based on hermeneutic tradition, the goal of this thesis is to further my understanding of what the concept of resistance means in a psychoanalytical context today, primarily within clinical practice. My methodology has been to seek an understanding of the concept of resistance by reading excerpts from the original texts of Sigmund Freud, as well as conducting interviews with practicing psychoanalysts that focus on how they relate to the notion of resistance. The idea was to then present my understanding of these sources in relation to one another. The results suggest that an understanding of the concept of resistance in a clinical context is highlighted by a dichotomy between theory and practice..

Tre metoder för diagnos av mastit i fält :

The objective of this work was to evaluate and compare three field methods for detection of mastitis, California Mastits Test (CMT), DeLaval cell counter DCC (DCC) and FMA2001 Farm Milk Analyzer (FMA2001). Furthermore, to investigate at what cell count level clinical symptoms of mastitis are seen, and finally to check if the clinical findings and cell counts could be related to bacteriological findings. DCC and FMA2001 are new analytic instruments to be used on dairy farms for detection of mastitis. CMT has been a widely used cow-side-test of milk quality in mastitis control efforts, but it cannot be used for estimating cell counts in scientific studies or investigations. Two hundred and eight quarter milk samples from 52 cows were analysed with DCC and CMT, and 168 of these samples with FMA2001. Microbiological examination was done on 38 milk samples with CMT scores of 4 and 5.

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